Rutherford came to national attention following World War II in the film adaptations of Noël Coward's Blithe Spirit, and Oscar Wilde's The Importance of Being Earnest. She won an Academy Award and a Golden Globe Award for her role as the Duchess of Brighton in The V.I.P.s (1963). In the early 1960s, she starred as Agatha Christie's character Miss Marple in a series of four George Pollock films.